Evidence Based Practice in Nursing: Purdue University School of Nursing

Comparison of Adverse Drug Events Data: Twitter Social Media Tweets versus Reports to the FDA FAERS System

This web site presents project posters from the Purdue University School of Nursing Evidence Based Practice in Nursing course in Fall 2016 taught by Professor Janet Thorlton. Each project poster compares adverse drug events (ADEs) for a specific drug described by data from Twitter social media tweets versus data reported to the FDA and documented in the FAERS system. Students used the SafeRx Database to query and analyze FAERS data.

The SafeRx project is a collaboration between the Center for Medication Safety Advancement (CMSA) at the College of Pharmacy and the Rosen Center for Advanced Computing at Purdue University.

Click on a drug name to view the student poster.


Project Authors:Whitney Stedman, Carly York, Samantha Walesky, Madeline Tutich
Project Description:Our group studied the prescription drug Olanzapine to collect data on the adverse effects talked about on social media versus FAERS data when used in treating Schizophrenia.
Project Authors: Kaitlyn Borowitz, Megan Bostick, Abbie Dralle, Rita Kendrick, Grace Malson, Annabelle Papai, Yi Tong
Project Description: Accutane is an oral drug that is used to treat severe nodular acne. It is a form of Vitamin A that decreases the amount of oil secreted by oil glands. Accutane was selected to be studied because it is commonly used among teenagers, and that age group uses Twitter more than other generations to express their thoughts. The top 15 adverse events (ADE) from Twitter were compared with the top 15 adverse effects from the FDA Adverse Event Reporting System (FAERS).
Project Authors: Claire Hornsby, Shelbie Huffmeyer, Taylor McBride, Ann Keimig
Project Description: Neurontin is a drug used for treating epilepsy and neuropathy. We compared SafeRx FAERS data and Twitter data on the adverse reactions for Neurontin. We were curious about the differences between reported adverse drug reactions on different platforms.
Project Authors: Carson Mulvehill, Kiley Wendt, Elizabeth Egan, Nicholas Moniz
Project Description: Depression is common among adolescents and quite prevalent in our society. On average, 1 in 6 people will experience depression at some stage in their life. Lexapro is an antidepressant of the selective serotonin reuptake inhibitor(SSRI) class used to treat depression and anxiety.
Project Authors: Allison Dugan, Sharon Benjamin, Brooke Wasserman, Maria Frenzel, Lindsey Haehl
Project Description: Adderall was selected because it is a commonly used drug among all age groups. The FDA Adverse Event Reporting System (FAERS) contains multiple reports of Adderall reactions. 300 tweets (ranging from 6/3/2014 - 10/26/2016) were collected to compare adverse effects to the reported FAERS data.
Project Authors: B. Connor, K. Joseph, A. Hershberger, J. Zielinski
Project Description: Zoloft was selected because it is a highly reported drug to the FDA Adverse Event Reporting System (FAERS). 300 tweets were randomly collected as a sample on 10/8/2016 with tweets with dates ranging from 12/7/15 - 10/8/16.
Project Authors: Jessica Stillson, Carolyn Wehman, Kaitlyn Schriver, Kara Gromnicki, Kiersten Smith, Lauren Kirwan
Project Description: Vyvanse was selected because it is one of the top drugs for treatment of ADHD. The top 300 tweets were chosen from Twitter as a sample on 10/17/2016 with tweets with dates ranging from 10/11/2016 to 10/19/2016.
Project Authors: Sarah Burgan, Nicolette De Micco, Alison Kiley, Abigail Rector, Lucy Schenkel
Project Description: We chose to use Zoloft because there were multiple adverse effects on both Twitter and within the FDA Adverse Event Reporting System. 300 tweets were randomly collected as a sample on 10/20/16 with tweets ranging from 09/04/16 to 10/17/16.
Project Authors: Emily Pawluk, Maria Touvannis, Jessica Helder, Sarah Myers
Project Description: Tamoxifen was selected because it is a common breast cancer drug for women battling breast cancer. Tamoxifen was frequently reported to the FDA Adverse Event Reporting System (FAERS). 300 tweets were randomly collected as a sample on 10/6/16 with tweets ranging from 12/6/13 to 10/5/16.
Project Authors:Sarah Leuther, Jeeeun Park, Anna Reed
Project Description: Prozac was selected because it is one of the most common antidepressants.
Project Authors: Megan Puckett, Megan Haan, Allison Nevill, Anna Shultz, Hannah Laffin, Isabelle Boeck
Project Description: Albuterol was chosen for its effectiveness in asthmatic patients; however, according to the FDA Adverse Event Reporting System (FAERS), there are many adverse effects reported with the use of this drug. 159 tweets were collected as a sample with dates ranging from 09/23/16 to 10/16/16 to compare the Twitter data with FAERS.
Project Authors: Sarah Rominger, Abby Mochel, Brianna Stephan, Brian Matejcak, Elise Guveiyian, Julie Harlow
Project Description: Prozac was chosen because it is one of many commonly prescribed antidepressants. 300 tweets were randomly collected between 10/18/2016 and 10/25/2016 including tweets posted between 10/17/2016 and 10/25/2016.
Project Authors: Sarah Rominger, Abby Mochel, Brianna Stephan, Brian Matejcak, Elise Guveiyian, Julie Harlow
Project Description: Zoloft was selected because it is a well-known selective serotonin reuptake inhibitor (SSRI) that is mainly used to treat depression. 300 tweets, with dates ranging from 7/28/16 to 10/10/16, were randomly selected as a sample on 10/10/16.