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Pattern Recognition for Normalized LC-MS Data

Posted 12 Jan, 2009 in Tools

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Available Versions

Supporting Documents

This tool is closed source.

Version 2.0 - published on 05 May. 2010
Contributor(s) Ann Christine Catlin
Rosen Center for Advanced Computing

George Howlett
Purdue University
At a glance This tool provides principal component analysis (PCA), linear discriminate analysis (LDA), and canonical discriminate analysis (CDA) for data clustering on aligned, normalized LC-MS datasets.
Screenshots
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Description

Pattern recognition approaches fall into two main categories: supervised and unsupervised. Supervised systems require knowledge or data in which the outcome or classification is known ahead of time, so that the system can be trained to recognize and distinguish outcomes. Unsupervised systems cluster or group records without previous knowledge of outcome or classification. The most frequently used unsupervised pattern recognition approach is principal component analysis (PCA). Other unsupervised methods include hierarchical clustering, k-means, and self organizing maps (SOM).

The Pattern Recognition Tool provides principal component analysis (PCA), linear discriminate analysis (LDA), and canonical discriminate analysis (CDA) for data clustering. The six graphics generated by the Tool are available in the results display window.

Input for the Pattern Recognition Tool includes:

  • the normalized data file generated from the Normalization Tool for a collection of LC-MS datasets aligned through the Peak Alignment Tool.
  • input parameters to provide information about the number of groups and group labels for the normalized dataset.



credits The pattern recognition software was developed by Xiang Zhang, Jiri Adamec, et al. in 2005. The Purdue Discovery Pipeline was created by the Bindley Biosciences Center under the direction of Charles Buck.
Cite this work

If you reference this work in a publication, please cite as follows:

  • Ann Christine Catlin; George Howlett (2009), "Pattern Recognition for Normalized LC-MS Data," http://ccehub.org/resources/pattern.

    BibTex | EndNote

Tags
  1. proteome discovery pipeline
  2. proteomics
  3. statistical models