Prelude Peptide Synthesizer Cleaning Instructions

22 Jan 2009 | Publications | Contributor(s): Aaron Masavage

This document contains a lab Parker Lab specific preventative maintenance procedure for: 1. Cleaning after each Synthesis 2. Monthly Cleaning

Case-control genome-wide association study of rheumatoid arthritis from Genetic Analysis Workshop 16 using penalized orthogonal-components regression-linear discriminant analysis

03 Mar 2010 | Publications | Contributor(s): Dabao Zhang, Min Zhang

Currently, genome-wide association studies (GWAS) are conducted by collecting a massive number of SNPs (i.e., large p) for a relatively small number of individuals (i.e., small n) and associations are made between clinical phenotypes and genetic variation one single-nucleotide polymorphism (SNP) at …

Simultaneous genome-wide association studies of anti-cyclic citrullinated peptide in rheumatoid arthritis using penalized orthogonal-components regression

03 Mar 2010 | Publications | Contributor(s): Min Zhang, Dabao Zhang

Genome-wide associations between single-nucleotide polymorphisms and clinical traits were simultaneously conducted using penalized orthogonal-components regression. This method was developed to identify the genetic variants controlling phenotypes from a massive number of candidate variants. By …

Penalized orthogonal-components regression for large p small n data

03 Mar 2010 | Publications | Contributor(s): Min Zhang, Dabao Zhang

Here we propose a penalized orthogonal-components regression (POCRE) for large p small n data. Orthogonal components are sequentially constructed to maximize, upon standardization, their correlation to the re-sponse residuals. A new penalization framework, implemented via empirical Bayes …

ITMIG Workshops on Prognostic Factors and Definitions, Policies and Procedures

14 Jan 2011 | Publications | Contributor(s): James Huang, Ann Christine Catlin

ITMIG conducted 2 workshops that took place at the Yale Cancer Center West Campus on November 15 and 16. The first workshop focused on a review of current data on prognostic factors, and potential new factors, while the second tackled areas of ambiguity, so that moving forward ITMIG would have a …

Behavior Lifestyle Questionnaire

09 Apr 2011 | Publications | Contributor(s): kathleen abrahamson, Meghan Heather McDonough

This questionnaire created by Kathleen Abrahamson and Meghan McDonough is used to collect physical activity, stress, social support, organizational and quality of life information for consented patients in the Colorectal Cancer Pilot Study. Kathleen Abrahamson, Department of Public Health , …