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Prelude Peptide Synthesizer Cleaning Instructions

22 Jan 2009 | Publications | Contributor(s):

This document contains a lab Parker Lab specific preventative maintenance procedure for: 1. Cleaning after each Synthesis 2. Monthly Cleaning

Case-control genome-wide association study of rheumatoid arthritis from Genetic Analysis Workshop 16 using penalized orthogonal-components regression-linear discriminant analysis

03 Mar 2010 | Publications | Contributor(s): Dabao Zhang, Min Zhang

Currently, genome-wide association studies (GWAS) are conducted by collecting a massive number of SNPs (i.e., large p) for a relatively small number of individuals (i.e., small n) and associations are made between clinical phenotypes and genetic variation one single-nucleotide polymorphism (SNP) at …

The Camp Calcium Database

23 Jun 2012 | Publications | Contributor(s): Corrie Marie Whisner, Sumudinie Fernando, Sudheera Ruwanthaka Fernando, Berdine Martin, Ann Christine Catlin, david michael grobe

Camp Calcium is a unique research study that investigates factors that improve building bone during the rapid growth period of adolescence and dietary factors which influence calcium and bone metabolism. While at camp, campers eat a controlled diet with a known amount of calcium and other …

Simultaneous genome-wide association studies of anti-cyclic citrullinated peptide in rheumatoid arthritis using penalized orthogonal-components regression

03 Mar 2010 | Publications | Contributor(s): Min Zhang, Dabao Zhang

Genome-wide associations between single-nucleotide polymorphisms and clinical traits were simultaneously conducted using penalized orthogonal-components regression. This method was developed to identify the genetic variants controlling phenotypes from a massive number of candidate variants. By …

Penalized orthogonal-components regression for large p small n data

03 Mar 2010 | Publications | Contributor(s): Min Zhang, Dabao Zhang

Here we propose a penalized orthogonal-components regression (POCRE) for large p small n data. Orthogonal components are sequentially constructed to maximize, upon standardization, their correlation to the re-sponse residuals. A new penalization framework, implemented via empirical Bayes …

ITMIG Workshops on Prognostic Factors and Definitions, Policies and Procedures

14 Jan 2011 | Publications | Contributor(s): James Huang, Ann Christine Catlin

ITMIG conducted 2 workshops that took place at the Yale Cancer Center West Campus on November 15 and 16. The first workshop focused on a review of current data on prognostic factors, and potential new factors, while the second tackled areas of ambiguity, so that moving forward ITMIG would have a …

Business Associate Agreements for the ITMIG Databases

03 Nov 2011 | Publications | Contributor(s): Ann Christine Catlin, James Huang, Frank Detterbeck, Sudheera Ruwanthaka Fernando, Sumudinie Fernando, Nasly Yoosuf, Ruchith, Ruwan Janapriya Egoda Gamage, Administrator ITMIG, Summer Guo, Xiaojie(Summer) Guo

The collection of BAAs for the ITMIG Databases will be stored here: Louis Pradel Hospital, Lyon, France Nicolas Girard 11.02.2011 Yale Cancer Center, New Haven, CT, USA Frank Detterbeck 11.07.2011 Memorial Sloan Kettering Cancer Center, New York, New York, USA Jim Huang …