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Lipidomics-Based Methods for Cancer Care Engineering

Posted 14 Oct, 2008 in Series

Abstract

Lidipomics is a relatively new field and the inclusion of this analysis in Cancer Care Engineering OMIC analyses represents a novel addition and provides great promise for increasing the value of the predictive statistical models that will be generated. While genomic, epigenomic, and proteomic approaches are being applied to the development of convenient and reliable biomarkers for CRC, a blood test with desired specificity and sensitivity for the early detection and reliable monitoring of disease progression has not been developed.

The Xu laboratory’s lipidomic approach will have an important and complimentary impact in this area. Xu’s studies have already shown that a group of lysophospholipids can detect CRC with high sensitivity and specificity. Confirmation and expansion of these studies will be pivotally important for the critical evaluation of the clinical usage of these biomarkers.

Cite this work

If you reference this work in a publication, please cite as follows:

  • (2008), "Lipidomics-Based Methods for Cancer Care Engineering," http://ccehub.org/resources/112.

    BibTex | EndNote

Tags
  1. lipidomics
  2. OMIC analysis

In This Series

Audio podcast
Video podcast

  1. Lipidomics Analysis Process

    14 Oct. 2008 | Teaching Materials

    The excel spreadsheet describes the lipidomics analysis process for negative and positive ion detection applied to five samples.

  2. Sample Preparation for Lipidomics Analysis

    14 Oct. 2008 | Animations

    This document describes the preparation of the plasma sample for lipidomics analysis using the API-4000 mass spectrometer. The plasma was processed from the patient whole blood at the IUSCC clinic immediately following sample acquisition.

  3. API-4000 Instrument Setup

    14 Oct. 2008 | PDF | Contributor(s): Ann Christine Catlin

    This document describes the setup for the API-4000 mass spectrometry instrument in preparation for lipidomics analysis of the plasma processed from the patient whole blood.