Samples (blood and tissue) and data (demographic, diagnosis and diet history) will be obtained from patients entering the Multidisciplinary Gastrointestinal Oncology Clinics at the IUSCC. A “SWAT” team of research nurses will be employed to:
Contact patients for consent to enter the CCE project and provide information and guidance regarding preparation for the first IUSCC clinic visit
Collect demographic and diet data
Draw and process blood during clinic visits following strictly proscribed protocols, and
Take responsibility for the integrity, annotation, storage and distribution of the processed blood samples and the demographic and diet data.
Documents describing the approved protocols, data gathering processes, and sample management for the Cancer Care Engineering Colorectal Cancer Study can be accessed here (see links to resources below). The documents include:
Protocol document approved by the IUSCC Institutional Review Board for the OMIC Pilot Study
Protocol descriptions and diagrams for sample acquisition, sample processing, and sample distribution,
Questionnaires used in the OMIC study to gather information about patients.
Processed samples will undergo SNP/Comet and lipidomic analysis at IUSCC OMIC research laboratories, and glycoproteomic and metabolomic analysis at Purdue University OMIC research laboratories.
