Colorectal Cancer Incidence Prediction Model

10 Jun. 2008 | Tools | Contributor(s): Eric Sherer, Mohd Rahmad

Stochastic simulation of polyp and colorectal cancer (CRC) incidence with patient age.

GCxGC MS Data Classification and Alignment

11 Jun. 2008 | Tools | Contributor(s): Dabao Zhang, Min Zhang, Jason Catlin

An OMIC data pre-processing tool for the M/Z classification and peak alignment of raw GCxGC-MS data.

Dust & Magnet - Interactive Visualization Tool to support decision making

10 Nov. 2008 | Animations | Contributor(s): Ji Soo Yi

We constantly run into complex decisions to make (e.g., such as buying a car) in daily lives. There are so many candidates and attributes to consider. However, we do not have proper tool to make sense of these complex data before making informed decisions. Using a magnet metaphor, Dust & …

Predicting Patient-specific CRC Incidence from Polyp Prevalence

17 Jun. 2008 | Teaching Materials | Contributor(s): Eric Sherer

Seminal work on CRC incidence modeling argued that the slope of the linear log-log CRC incidence with age implies that 6 or 7 somatic mutations are required for transformation to CRC. Subsequent modeling efforts have built on this theme by using models of linear, sequential transformations for …

Cancer Care Life-Cycle/Continuum

19 Jun. 2008 | Online Presentations | Contributor(s): Seza Orcun

This presentation gives an abstract overview of the Cancer Care Life-Cycle Continuum.Dr. Aydogan-Cremaschi, Purdue University, Discovery Park Dr. Cripe, Indiana University, School of Medicine Dr. B. Doebbeling, Indiana University, School of Medicine Dr. C. Doebbeling, Indiana University, School …

A Multi-Agent Approach to Modeling of the Indiana CRC Care System

19 Jun. 2008 | Online Presentations | Contributor(s): Selen Cremaschi

This presentation introduces one of the projects from the cancer care engineering portfolio. It focuses on colorectal cancer care system modeling using a multi-agent based approach. The project methodology and its current state are explained. Tapas Das, PhD (USF) Brad Doebbeling, MD, MSc, FACP …

Cancer Care Engineering : A Collaborative Transformational Project

19 Jun. 2008 | Online Presentations | Contributor(s): Joseph Pekny, Marietta Harrison

The Cancer Care Engineering (CCE) project focuses on applying system engineering principles to the cancer problem. The initial focus is on colon cancer. The project has two main goals: to identify molecular signatures in blood that are predictive for colon cancer development, progression and …

Monte Carlo Simulation for four CRC Incidence Models

16 Jul. 2008 | Tools | Contributor(s): Eric Sherer

A Monte Carlo Simulator determines the risk of colorectal cancer (CRC) development in a population by calculating multiple, individual patient trajectories.

Workspace

17 May. 2008 | Tools

Linux desktop running in your web browser

Cancer Care Engineering Retreat 2008

28 Aug. 2008 | Series | Contributor(s): Julie Nagel

The 3rd Annual Cancer Care Engineering Retreat was held in Lebanan, Indiana on June 20, 2008. The Retreat Agenda included presentations by Joe Pekny, Marietta Harrison, Brad Doebbling, Julie Nagel, Gabi Chiorian, Stan Hamilton, David Ebert, Ann Christine Catlin and Reha Uzsoy. Video of the retreat …

CCE Retreat 2008 Part I

28 Aug. 2008 | Online Presentations | Contributor(s): Marietta Harrison, Joseph Pekny

Cancer Care Engineering Retreat Video Part I. (one hour) The following presentations are included in the video: Marietta Harrison, Director, Oncological Sciences Center, Purdue University. Introduction and Overview. (00:00-3:00) Introduction of all Retreat Participants. (3:01-11:40) Joe Pekny, …

CCE Retreat 2008 Part II

28 Aug. 2008 | Online Presentations | Contributor(s): Julie Nagel

Cancer Care Engineering Retreat Video Part II. (one hour) The following presentations are included in the video: Gabi Chiorean, MD, Indiana University School of Medicine, Hematology/Oncology. Clinical Aspects of Protocol.(00:00-15:35) (no powerpoint presentation) Stan Hamilton, MD, Professor of …

CCE Retreat 2008 Part III

28 Aug. 2008 | Online Presentations | Contributor(s): Ann Christine Catlin, David Ebert

Cancer Care Engineering Retreat Video Part III. (one hour) The following presentations are included in the video: Stan Hamilton, MD. Professor of Pathology. MD Anderson Cancer Care Center. (continued) Advances in Colorectal Cancer Biomarker Discovery. (00:00-7:35) David Ebert, Professor of …

CCE Retreat 2008 Part IV

28 Aug. 2008 | Online Presentations | Contributor(s): Ann Christine Catlin, Eric Sherer, Julie Nagel

Cancer Care Engineering Retreat Video Part III. (one hour) The following presentations are included in the video: Ann Christine Catlin, Research Scientist, Rosen Center for Advanced Computing, Purdue University. (continued) The cceHUB as a Research Tool. (00:00-15:04) Eric Sherer, Medical …

CCE Retreat 2008 Part V

28 Aug. 2008 | Online Presentations | Contributor(s): Julie Nagel

Cancer Care Engineering Retreat Video Part V. (one hour) The following presentations are included in the video: Reha Uzsoy, PhD, Clifton A. Anderson Distinguished Professor, Edward P. Fitts Department of Industrial and Systems Engineering, North Carolina State University . Systems Approach to …

Visual Analytics for Cancer Care Engineering

29 Aug. 2008 | Teaching Materials | Contributor(s): David Ebert

The Purdue University Regional Visualization and Analytics Center (PURVAC) presents a visual analytics tool for analyzing GCxGC TOF Mass Spectrometry data for metabolomics samples.

A Hierarchical System Based Approach to Improving Cancer Care

29 Aug. 2008 | Teaching Materials | Contributor(s): Ann Christine Catlin

The presentation title is "Developing a Hierarchical System Based Approach to Improving Cancer Care: Establishing an Indiana Prototype for Next-generation Colorectal Cancer Care". The Cancer Care Engineering (CCE) hierarchy of projects proposes a methology for improving cancer care and directing …

Syndromic Surveillance Hypothesis Development Using Visual Analytics

09 Sep. 2008 | Downloads | Contributor(s): Ross Maciejewski, David Ebert

When analyzing syndromic surveillance data, health care officials look for areas with unusually high cases of syndromes. Unfortunately, many outbreaks are difficult to detect because their signal is obscured by the statistical noise. Consequently, many detection algorithms have a high false …

CANCER CARE ENGINEERING OF COLORECTAL CANCER – OMICs PILOT STUDY

29 Sep. 2008 | Teaching Materials | Contributor(s): Julie Nagel

Protocol IUCRO-0221 submitted to the Scientific Review Committee of the Indiana University Simon Cancer Center Institutional Review Board on February 28, 2008.Gabi Chiorean, M.D.

New Faculty Orientation Luncheon at Purdue University

17 Sep. 2008 | Online Presentations | Contributor(s): Joseph Pekny, Marietta Harrison

Professors Joseph Pekny and Marietta Harrison present the Cancer Care Engineering hierarchy of projects to the new faculty at the orientation luncheon in August, 2008 at Purdue University.Joe Pekny, Professor Chemical Engineering; Director e-Enterprise Center Discovery Park Marietta Harrison, …

NCI Diet History Questionnaire

29 Sep. 2008 | Downloads | Contributor(s): Julie Nagel

The Diet History Questionnaire (DHQ) is a food frequency questionnaire (FFQ) developed by staff at the Risk Factor Monitoring and Methods Branch (RFMMB) at NCI. This FFQ consists of 124 food items and includes both portion size and dietary supplement questions. It takes about 1 hour to complete and …

CRC Sample Processing for Cancer Care Engineering

30 Sep. 2008 | Notes | Contributor(s): Julie Nagel, Ann Christine Catlin

Blood samples will be obtained from patients undergoing colonoscopies at the Indiana University Medical Center. Blood samples will also be obtained from spouses or household companions (non-cancer control samples). Once colonoscopy results are read, samples will be labeled as normal, polyp, or …

Introduction to Population Balance Modelling

01 Oct. 2008 | Teaching Materials | Contributor(s): Eric Sherer

This presentation gives an overview of the role and applications of population balance (or structured) models in describing biological phenomenon. These models represent the continuum between purely empirical models and mechanistic models where details are often lumped into the structured …

Lifestyle Exposure Questionnaire

02 Oct. 2008 | Downloads | Contributor(s): Julie Nagel

This questionnaire will be adminstered to all consented patients to collect information on their lifestyle and environmental exposures.James Klaunig, PhD, Associate Director, IU Simon Cancer Center, Director, Center for Environmental Health

Metabolomics-Based Methods for Biomarker Discovery of Disease

06 Oct. 2008 | Downloads | Contributor(s): Daniel Raftery

The presentation gives an overview of metabolomics and Cancer Care Engineering. The combination of NMR and multivariate statistical analysis is providing a new way to analyze complex samples such as biofluids. The field of metabolite profiling or "metabolomics" has significant implications for …